19275-51-5

Cyclomulberrin is a extended flavonoid that shows inhibition of arachidonic acid (AA)- and collagen-induced platelet aggregation, with IC50 value of 128.2 μM[1][2].

ChEBI: A extended flavonoid that is 6H,7H-chromeno[4,3-b]chromen-7-one which is substituted by a 2-methylprop-1-en-1-yl group at position 6, a 3-methylbut-2-en-1-yl group at position 11, and hydroxy groups at pos tions 3, 8, and 10. It is found in the bark of Morus species and has been reported to protect human neuronal cells derived from the human neuroblastoma SH-SY5Y cell line.

[1] V.H. Deshpande, et al. Four analogues of artocarpin and cyclotocarpin from morus alba. 9(14), 1715–1719.
[2] Chun-Nan Lin, et al. Antiplatelet activity of some prenylflavonoids. Biochem Pharmacol. 1993 Jan 26;45(2):509-12. PMID:8435100