1926163-16-7

Glp-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-Gly-Leu-Arg-Pro-Gly-NH2 ([D-Trp6]-LH-RH-Leu-Arg-Pro-Gly-NH2) is a GnRH (gonadotropin-releasing hormone) agonisttriptorelin. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2)which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelinis crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropinsluteinizing hormone (LH) and follicle-stimulating hormone (FSH)from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Triptorelin is used for the treatment of hormone-associated prostate and breast cancersendometriosisuterine fibroidscentral precocious puberty and in vi