Uses
Methyl 6-aminohexanoate is used as a reagent to synthesize straight chain hydroxamates, compounds that act as inhibitors of Human Histone Deacetylase (HDAC) that have the potential to treat cancer. Methyl 6-aminohexanoate is also sometimes used as a spacer unit for peptide synthesis.
References
[1] Journal of Medicinal Chemistry, 2001, vol. 44, # 26, p. 4737 - 4740
[2] Journal of Medicinal Chemistry, 2015, vol. 58, # 16, p. 6516 - 6532
[3] Journal of Medicinal Chemistry, 2006, vol. 49, # 20, p. 6094 - 6103
[4] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 16, p. 5950 - 5961
[5] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 15, p. 3591 - 3594
