192581-24-1

Name	BIIL-260 hydrochloride
CAS	192581-24-1
Molecular Formula	C30H31ClN2O3
MDL Number	MFCD20267599
Molecular Weight	503.04
MOL File	192581-24-1.mol

Synonyms

BIIL-260 hydrochloride

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Chemical Properties

storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	Solid
color	White to off-white

Hazard Information

Uses

BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with Ki values of 1.7 nM[1].

IC 50

LTB₄: 1.7 nM (Ki)

References

[1] Birke FW, et al. In vitro and in vivo pharmacological characterization of BIIL 284, a novel and potent leukotriene B(4) receptor antagonist. J Pharmacol Exp Ther. 2001 Apr;297(1):458-66. PMID:11259574

Supplier

Fan De(Beijing) Biotechnology Co., Ltd.

Telephone 15911056312

Websitehttp://www.bio-fount.com/

Wuhan Yuxiang Medical Technology Co., Ltd.

Telephone 13971275651

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList1155268/0_EN.htm

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Biosynth Biological Technology (Suzhou) Co Ltd

Telephone 51288865780

Websitehttp://www.biosynth.com

Adooq Bioscience LLC

Telephone400-025-6535

Websitehttp://www.adooq.cn

Guangzhou Xinrui Biotechnology Co., Ltd.

Telephone18027212158

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList1865991/0_EN.htm

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