192130-34-0

227776-28-5

192130-34-0

GENERAL METHOD: N-substituted phthalimide (2.00 mmol) was mixed with 80% aqueous hydrazine hydrate (2 mL) in ethanol (20 mL) and the reaction was stirred at 70°C for 20 hours. After completion of the reaction, the mixture was cooled to room temperature and filtered to remove the precipitate. The filtrate was concentrated under reduced pressure to remove the solvent to give the crude product, which can be used directly in subsequent reactions without further purification.