ChemicalBook CAS DataBase List 189035-07-2

189035-07-2

Name	(11β,17β)-11-(1,3-Benzodioxol-5-yl)-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one
CAS	189035-07-2
Molecular Formula	C28H30O4
MDL Number	MFCD07772248
Molecular Weight	430.54
MOL File	189035-07-2.mol

Chemical Properties

Boiling point	621.0±55.0 °C(Predicted)
density	1.29±0.1 g/cm3(Predicted)
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Sparingly)
form	Solid
pka	12.89±0.60(Predicted)
color	White to Off-White

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Animal Model:	C57Bl/6 mice (2.5 mg/kg/day rotenone by intraperitoneal injection for 14 days)^[2]
Dosage:	30, 100 mg/kg
Administration:	P.o.; daily for 14 days
Result:	Reduced the loss of dopaminergic neuron (DAn) cell bodies in the substantia nigra (SN), but not the striatum, and prohibited intra-neuronal accumulation of α-synuclein (α-syn).