ChemicalBook CAS DataBase List 187325-53-7

187325-53-7

Name	2H-Indol-2-one, 1,3-dihydro-3-(2-pyridinylmethylene)-, (3Z)-
CAS	187325-53-7
Molecular Formula	C14H10N2O
MDL Number	MFCD00435358
Molecular Weight	222.24
MOL File	187325-53-7.mol

Chemical Properties

Boiling point	457.2±45.0 °C(Predicted)
density	1.291±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	Solid
pka	12.34±0.20(Predicted)
color	Yellow to orange

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Animal Model:	HFD+STZ diabetic rats ^[1].
Dosage:	50 mg/kg
Administration:	i.p., 30 min prior to glucose challenge
Result:	Vehicle-treated diabetic rats developed persistent hyperglycemic response. Administration of GSK-3β inhibitor 1 30 min prior to glucose challenge effectively prevented increase in blood glucose levels.

187325-53-7

Chemical Properties

Hazard Information

Uses

in vivo

IC 50

storage

References

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