1862238-01-4

MZ-242 is a potent and selective Sirt2 inhibitor.

Sirt2-IN-2 (Compound 10) is a selective Sirt2 inhibitor with an IC50 of 0.118 μM[1].

[1] Schiedel M, et al. Structure-Based Development of an Affinity Probe for Sirtuin?2. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6. DOI:10.1002/anie.201509843