183364-82-1

(RS)-CPPG is the most potent group II/III mGluR antagonist.

ChEBI: 2-amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid is an alpha-amino acid.

Potent group II/III mGlu receptor antagonist, with approximately 20-fold selectivity for group III over group II (IC 50 values of 2.2 and 46.2 nM respectively). A much less potent antagonist at group I receptors in neonatal rat cortical slices (K b = 0.65 ± 0.07 nM). Also available as part of the Group III mGlu Receptor Tocriset™ .

Room temperature