ChemicalBook CAS DataBase List 1816331-63-1

1816331-63-1

Chemical Properties

Melting point	>120°C (dec.)
Boiling point	704.2±60.0 °C(Predicted)
density	1.35±0.1 g/cm3(Predicted)
storage temp.	-20°C Freezer, Under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	12.26±0.70(Predicted)
color	White to Pale Yellow

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Hubei Kele Fine Chemical Co., Ltd

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Beijing Biocreative Technology Co., Ltd.

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TargetMol Chemicals Inc.

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Biosynth Biological Technology (Suzhou) Co Ltd

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Websitehttp://www.biosynth.com

Shanghai Amole Biotechnology Co., Ltd.

Telephone18017925202 18916960931

Websitehttps://www.amole.com.cn/

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Animal Model:	Male CD-1 mice with IDH1 mutant AML xenograft^[1]
Dosage:	150 mg/kg
Administration:	Intraperitoneal injection; daily, for 15 days
Result:	Decreased in 2HG in IDH1-mutant AML cells. Decreased in the percentage of blast cells (^SSClowCD45^low/+) and a relative increase in mature lymphoid and granulocytic/monocytic cells.