180313-86-4

Z-FG-NHO-BzOME is a cysteine protease inhibitor that selectively inhibits cathepsin B, cathepsin L, cathepsin S, and papain[1].

Cell permeable: no''Primary Target
cathepsin B''Product does not compete with ATP.''Reversible: no''k2/Ki = 1 x 10⁴ M-¹ sec-¹

[1] Rajgopal Yadavalli, et al. Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation. J Biol Chem. 2004 May 21;279(21):21948-56. DOI:10.1074/jbc.M400793200