1802497-05-7

Terrelumamide A is a lumazine-containing peptide. Terrelumamide A is isolated from the culture broth of the marine-derived fungus Aspergillus terreus. Terrelumamide A exhibits pharmacological activity by improving insulin sensitivity. Terrelumamide A has the potential in the application of DNA sequence recognition[1].

Terrelumamide A is a lumazine-containing peptide fungal metabolite originally isolated from A. terreus.1 It increases adiponectin production, a marker of insulin sensitivity, in human bone marrow mesenchymal stem cells (hBM-MSCs; EC50 = 37.1 μM).

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|1. You, M., Liao, L., Hong, S.H., et al. Lumazine peptides from the marine-derived fungus Aspergillus terreus. Mar. Drugs 13(3), 1290-1303 (2015).