1,2-Didecanoylglycerol, a synthetic diacylglycerol, is metabolized by platelets to 1,2-didecanoylphosphatidic acid (PA10) and activates protein kinase C (PKC)[1][2].
Definition
ChEBI: 1,2-didecanoylglycerol is a 1,2-diglyceride and a decanoate ester.
References
[1] Lapetina EG. Incorporation of synthetic 1,2-diacylglycerol into platelet phosphatidylinositol is increased by cyclic AMP. FEBS Lett. 1986;195(1-2):111-114. DOI:10.1016/0014-5793(86)80141-7 [2] Negro-Vilar A, et al. 1,2-Didecanoylglycerol and phorbol 12,13-dibutyrate enhance anterior pituitary hormone secretion in vitro. Endocrinology. 1985;117(4):1559-1564. DOI:10.1210/endo-117-4-1559
