170508-05-1

Lanepitant dihydrochloride (LY303870 dihydrochloride) is a non-peptide neurokinin-1 receptor antagonist. Lanepitant dihydrochloride has analgesic and anti-inflammatory activities[1][2].

[1] Goldstein DJ, et al. Lanepitant, an NK-1 antagonist, in migraine prevention. Cephalalgia. 2001 Mar;21(2):102-6. DOI:10.1046/j.1468-2982.2001.00161.x
[2] Goldstein DJ, et al. Study of the analgesic effect of lanepitant in patients with osteoarthritis pain. Clin Pharmacol Ther. 2000 Apr;67(4):419-26. DOI:10.1067/mcp.2000.105243