1668-86-6

Name (+/-)-Narwedine
CAS 1668-86-6
Molecular Formula C17H19NO3
MDL Number MFCD13193038
Molecular Weight 285.341
MOL File 1668-86-6.mol
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Chemical Properties

Melting point  198-199 °C(Solv: ethyl acetate (141-78-6))
Boiling point  397.4±42.0 °C(Predicted)
density  1.28
pka 7.84±0.20(Predicted)
InChI InChI=1/C17H19NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,14H,7-10H2,1-2H3/t14-,17-/s3
InChIKey QENVUHCAYXAROT-OALMKZFLNA-N
SMILES N1(C)CC2=CC=C(OC)C3O[C@@]4([H])[C@](C=CC(=O)C4)(C2=3)CC1 |&1:11,13,r|
Uses
Narwedine is the biogenetic precursor of galanthamine, has been studied as a respiratory stimulator. It increases the amplitude and decreases the frequency of cardiac contractions and would therefore be of value in reducing blood loss during surgery. It also inhibits the action of narcotics and hypnotics, and increases the analgesic effect of morphine as well as the pharmacological effects of caffeine, carbazole, arecoline, and nicotine.
CAS DataBase Reference 1668-86-6

Safety Data

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H319-H412
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P273-P501
REACH Registrations Inactive

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