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Pro-Phe-Phe is the most aggregation-prone tripeptide of natural amino acids. Pro-Phe-Phe forms unique helical-like sheets that mate via aromatic dry interfaces. Pro-Phe-Phe can be used for the design of modular super-helical self-assembling nanostructures[1][2].

ChEBI: Pro-Phe-Phe is an oligopeptide.

[1] Bera S, et, al. Rigid helical-like assemblies from a self-aggregating tripeptide. Nat Mater. 2019 May;18(5):503-509. DOI:10.1038/s41563-019-0343-2