1631164-24-3

BAY-784 is a gonadotropin releasing hormone receptor (GnRH-R) antagonist probe with IC50s of 21 and 24 nM for human and rat GnRH-R, respectively[1].

BAY-784 is an orally availablenon-toxicpotentand selective antagonist of human Gonadotropin-Releasing Hormone Receptor [hGnRH-R]which is potently active in other species including ratedogs and cynomolgus monkey. It partially lowered plasma luteinizing hormone levels in humans. BAY-784 exhibits favorable drug metabolism and pharmacokinetic (DMPK) profile thus is suitable for in vivo studies.

[1] GnRH-R Antagonist Probe BAY-784.