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A1B11 is a SIRT2-selective inhibitor.

A1B11 is a selective SIRT inhibitor (SIRT2:IC50=5.3 μM) that can be used in the study of neurodegenerative diseases[1].

SIRT2: 5.3 μM (IC₅₀)

[1] Tatum P R, et al. Identification of novel SIRT2-selective inhibitors using a click chemistry approach[J]. Bioorganic & medicinal chemistry letters, 2014, 24(8): 1871-1874. DOI:10.1016/j.bmcl.2014.03.026