159730-09-3

7-fluoro Tryptamine is a tryptamine derivative that potentially agonizes 5-HT serotonin receptors. Although the biological effects of this compound have not been reported, certain hallucinogenic typtamines containing a fluorine substitution at the 5-, 6-, or 7-position have been shown to have 5-HT_2C receptor selectivity over both the 5HT_2A and 5-HT_2B subtypes.^1,2 This product is intended for research and forensic applications.

7-Fluorotryptamine hydrochloride is a potent agonist of GPRC5A. 7-Fluorotryptamine hydrochloride induces GPRC5A-mediated β-arrestin recruitment. 7-Fluorotryptamine hydrochloride can be used for research of immune and cancer signaling[1].

1. Kalir, A., and Szara, S. Synthesis and pharmacological activity of fluorinated tryptamine derivatives J. Med. Chem. 6(6),716-719(1963).
2. Blair, J.B., Kurrasch-Orbaugh, D., Marona-Lewicka, D., et al. Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines J. Med. Chem. 43(24),4701-4710(2000).