159518-97-5

Cloransulam is used as a herbicide for weed control in agriculture.

ChEBI: A sulfonamide resulting from the formal condensation of the sulfonic acid group of 5-ethoxy-7-fluoro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonic acid with the amino group of 2-amino-3-chlorobenzoic acid. The methyl ester of cloransulam, general y known as cloransulam-methyl, is used as a herbicide for the control of post-emergence control of broad-leaved weeds in soybeans.

Cloransulam is manufactured through the standard sulfonamide-herbicide route, in which the key heterocyclic core is built first and then coupled to the sulfonamide fragment. Commercial producers begin by constructing the triazolopyrimidine scaffold, introducing the chloro and methoxy substituents through controlled heterocycle-forming and substitution steps. This heterocycle is then reacted with the appropriate benzenesulfonamide derivative under conditions that promote selective sulfonamide bond formation, yielding technical-grade cloransulam.

Inhibits plant amino acid synthesis - acetohydroxyacid synthase AHAS.

Herbicide