158198-48-2

Chir 4531 is a N-(substituted)glycine peptoid trimer.

CHIR 4531, a trimer peptide, is a opiate ligand that binds to the mu-opiate receptor with a Ki of 6 nM[1].

μ Opioid Receptor/MOR: 6 nM (Ki)

[1] R N Zuckermann, et al. Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library. J Med Chem. 1994 Aug 19;37(17):2678-85. DOI:10.1021/jm00043a007