156473-26-6

11(S)-HEPE is a monohydroxy fatty acid derived from EPA, theoretically by the action of COX. Although its arachidonate derived congener 11(S)-HETE has been isolated from cultured neutrophils, it is not known if similar incubations with EPA can produce 11(S)-HEPE.¹

ChEBI: 11S-HEPE is a HEPE.

1. Myers, R.F., and Siege, M.I. Differential effects of anti-inflammatory drugs in lipoxygenase and cyclo-oxygenase activities of neutrophils from a reverse passive arthus reaction Biochem. Biophys. Res. Commun. 112,586-594(1983).