155204-09-4

(S)-Hydroxychloroquine is an isomer of hydroxychloroquine .1 (S)-Hydroxychloroquine (2.5-20 mg/ml) reduces the rate of insulin degradation in isolated liver homogenates from non-diabetic and diabetic rats. Formulations containing hydroxychloroquine have been used in the prevention or treatment of malaria, as well as in the treatment of rheumatoid arthritis and systemic lupus erythematosus.

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1.Emami, J., Pasutto, F.M., Mercer, J.R., et al.Inhibition of insulin metabolism by hydroxychloroquine and its enantiomers in cytosolic fraction of liver homogenates from healthy and diabetic ratsLife Sci.64(5)325-335(1999)