1537889-10-3

JWH 398 is a synthetic cannabinoid (CB) that acts as an agonist at both the central CB₁ receptor and the peripheral CB₂ receptor (K_is = 2.3 and 2.8 nM, respectively).¹ It has been detected as an additive of herbal mixtures.² JWH 398 N-pentanoic acid metabolite is an expected phase I metabolite of JWH 398. The biological and toxicological properties of this compound have not been characterized. This product is intended for forensic and research purposes.

1. Huffman, J.W. Cannabimimetic indoles, pyrroles, and indenes: Structure-activity relationships and receptor interactions The cannabinoid receptors ,49-95(2009).
2. Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y. Survey of current trends in the abuse of psychotropic substances and plants in Japan Leg. Med. (Tokyo) 13(3),109-115(2011).