Description
JWH 203 is a synthetic cannabinoid (CB) that displays high affinities for both the central CB
1 receptor (K
i = 8.0 nM) and the peripheral CB
2 receptor (K
i = 7.0 nM).
1 JWH 203 N-
pentanoic acid metabolite is an expected metabolite of JWH 203, based on the metabolism of similar compounds.
2 The physiological and toxicological properties of this compound have not been characterized. This product is intended for forensic and research purposes.
References
1. Huffman, J.W., Szklennik, P.V., Almond, A., et al. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles Bioorg. Med. Chem. Lett. 15(18),4110-4113(2005).
2. Moran, C.L., Le, V.H., Chimalakonda, K.C., et al. Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine Anal. Chem. 83(11),4228-4236(2011).