(S)-Alprenolol hydrochloride is a potent and nonselective β-blocker[1].
References
[1] K M H?ld, et al. Enantioselective quantitation of (R)- and (S)-alprenolol by gas chromatography-mass spectrometry in human saliva an plasma. J Chromatogr Sci. 1996 Jan;34(1):13-9. DOI:10.1093/chromsci/34.1.13