150461-07-7

L 691816 is a potent inhibitor of the 5-LO reaction both in vitro and in a range of in vivo models.

L 691816 is a potent, selective and orally active inhibitors of 5-lipoxygenase. L 691816 can be used for the research of allergies and asthma[1].

[1] Hutchinson JH, et, al. Substituted thiopyrano[2,3,4-c,d]indoles as potent, selective, and orally active inhibitors of 5-lipoxygenase. Synthesis and biological evaluation of L-691,816. J Med Chem. 1993 Sep 17;36(19):2771-87. DOI:10.1021/jm00071a008