1494477-03-0

PSB-1410 is a potent, selective, competitive, and reversible inhibitor of monoamine oxidase B (MAO-B).

PSB-1410 is a selective and competitive monoamine oxidase B (MAO-B) inhibitor with IC50 for human MAO-B and rat MAO-B Values are 0.23 and 1.01 nM respectively[1].

hMAO-B: 0.23 nM (IC₅₀); rMAO-B: 1.01 nM (IC₅₀)

[1] Tzvetkov NT, et al. Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency. J Med Chem. 2014 Aug 14;57(15):6679-703. DOI:10.1021/jm500729a