1483-56-3

off-white powder

2-Bromo-5-(trifluoromethyl)benzoic acid is used as an organic synthesis reagent or pharmaceutical intermediate compound.

2,2,6,6-tetramethylhexahydropiperidine (22.5 ml, 133.4 mmol) was added to a solution of n-BuLi (26.7 ml of a 2.5 M solution in tetrahydrofuran (THF), 66.7 mmol) in THF (130 ml) at -78 °C. The mixture was stirred at -78 °C for 30 min and then carefully low