146478-73-1

FR901465 is a potent anti-cancer and anti-tumor agent. FR901465 can be used for cancer research[1].

ChEBI: A spiro-epoxide with potent cytotoxic activity against human tumour cells. It is isolated from Pseudomonas sp. no.2663.

[1] H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action. J Antibiot (Tokyo). 1996 Dec;49(12):1204-11. DOI:10.7164/antibiotics.49.1204
[2] H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. III. Structures of FR901463, FR901464 and FR901465. J Antibiot (Tokyo). 1997 Jan;50(1):96-9. DOI:10.7164/antibiotics.50.96
[3] Ratnakar N. Asolkar, et al. Discovery and Development of Natural Products for Pest Management. RETURN TO BOOKPREVCHAPTERNEXT