1429624-84-9

PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor with an IC50 of 7 nM. PI4KIIIbeta-IN-9 also inhibits PI3Kδ and PI3Kγ with IC50s of 152 nM and 1046 nM, respectively.

PI4KIIIβ: 7 nM (IC₅₀); PI4KIIIα: 2.6 μM (IC₅₀); PI3Kδ: 152 nM (IC₅₀); PI3Kγ: 1046 nM (IC₅₀); PI3Kα: 2 μM (IC₅₀); PI3KC2γ: 1 μM (IC₅₀)

Store at -20°C

[1] Rutaganira FU, et al. Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ. J Med Chem. 2016 Mar 10;59(5):1830-9. DOI:10.1021/acs.jmedchem.5b01311