Identification Chemical Properties Safety Data

1422-07-7

Name CODEINE HYDROCHLORIDE
CAS 1422-07-7
EINECS(EC#) 215-829-5
Molecular Formula C18H22ClNO3
MDL Number MFCD00153029
Molecular Weight 335.83
MOL File 1422-07-7.mol
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Chemical Properties

Appearance White or almost white, crystalline powder or small, colourless crystals.
Melting point  ~280° with some decompn
alpha  D22 -108°
Contact allergens
Codeine has been reported as an occupational sensitizer in workers in the production of opium alkaloids. Codeine has been responsible for fixed drug eruptions or generalized dermatitis. Cross-sensitivity is expected to morphine.
Uses
Opioid receptor agonist; analgesic.

Safety Data

Symbol(GHS) 
GHS07,GHS05
Signal word  Danger
Hazard statements  H302-H362-H318-H317
Precautionary statements  P280-P305+P351+P338-P310-P201-P260-P263-P264-P270-P308+P313-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501
Toxicity
LD50 s.c. in mice: 300 mg/kg (Eddy, Sumwalt)
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