ChemicalBook CAS DataBase List 1421448-26-1

1421448-26-1

Name	N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine
CAS	1421448-26-1
Molecular Formula	C18H15N3O2
MDL Number	MFCD30182340
Molecular Weight	305.33
MOL File	1421448-26-1.mol

Chemical Properties

Melting point	144 - 148oC
Boiling point	543.7±50.0 °C(Predicted)
density	1.421±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer, Under inert atmosphere
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	14.30±0.20(Predicted)
color	Pale Brown

Safety Data

WGK Germany	WGK 3
Storage Class	11 - Combustible Solids

Hazard Information

Spectrum Detail

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Animal Model:	Mice bearing a mixed orthotopic tumor with PN12 and ME23 cells^[3]
Dosage:	10 mg/kg
Administration:	Oral gavage
Result:	Reduced both proneural and mesenchymal markers.

Animal Model:	Subcutaneous colorectal cancer model (HCT116)^[2]
Dosage:	5 mg/kg
Administration:	Tail vein injection, twice a week
Result:	Reduced pulmonary nodules in tumor-bearing mice, and enhanced the outcome of chemotherapy.

1421448-26-1

Chemical Properties

Safety Data

Hazard Information

Uses

Biological Activity

in vivo

storage

Spectrum Detail

Supplier

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