1404559-91-6

BRD4884 is a selective HDAC2 inhibitor. It acts by enhancing the learning and memory processes.

BRD4884 is a potent HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1.09 μM for HDAC1, 2, and 3, respectively[1].

HDAC1: 29 nM (IC₅₀); HDAC2: 62 nM (IC₅₀); HDAC3: 1.09 μM (IC₅₀)

[1] Wagner FF, et al. Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers. Chem Sci. 2015 Jan 1;6(1):804-815. DOI:10.1039/C4SC02130D