14042-01-4

Peroxynitrite has been used to induce pericyte contraction in mouse brains. It has also been used for the preparation of positive control nitrated protein standards in immunohistochemical studies.

Peroxynitrite (ONOO-) exhibits bactericidal activity. It promotes cell death and contributes to the signal-transduction processmitochondrial functionand apoptotic pathway. The formation of peroxynitrite has been associated with the development of various diseases including vascular diseasesischemia-reperfusion injurycirculatory shockinflammationpainand neurodegeneration.