ChemicalBook CAS DataBase List 1398609-39-6

1398609-39-6

Name	Sarolaner
CAS	1398609-39-6
Molecular Formula	C23H18Cl2F4N2O5S
MDL Number	MFCD28963963
Molecular Weight	581.36
MOL File	1398609-39-6.mol

Chemical Properties

Boiling point	722.7±70.0 °C(Predicted)
density	1.65±0.1 g/cm3(Predicted)
storage temp.	Store at 4°C, sealed storage, away from moisture
solubility	DMF: Slightly soluble; DMSO: Slightly soluble; Ethanol: Slightly soluble
form	A solid
pka	-0.93±0.20(Predicted)
color	White to off-white
InChIKey	FLEFKKUZMDEUIP-QFIPXVFZSA-N
SMILES	C(=O)(N1CC2(C3=C(C=C(C4C[C@](C5=CC(Cl)=C(F)C(Cl)=C5)(C(F)(F)F)ON=4)C=C3)CO2)C1)CS(C)(=O)=O

Safety Data

Symbol(GHS)	GHS07,GHS09
Signal word	Warning
Hazard statements	H400-H302-H410
Precautionary statements	P264-P270-P301+P312-P330-P501-P273-P391-P501-P273-P391-P501

Hazard Information

Spectrum Detail

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Animal Model:	Dog infested with R. sanguineus and D. reticulatus^[1]
Dosage:	2.5 mg/kg
Administration:	Oral gavage; 2.5 mg/kg once
Result:	Exibited 100% efficacy against R. sanguineus at 48 hours after treatment and also exhibited 98.0% efficacy againstD. reticulatus.

Animal Model:	Dog infested with I. ricinus^[1]
Dosage:	1.25, 2.5 and 5 mg/kg
Administration:	Oral gavage; 1.25, 2.5 and 5 mg/kg once
Result:	Exibited 100% efficacy against I. ricinus at all doses until 7 days, and provided over 99.3% reduction against subsequent re-infestations until 57 days at dose of 5.0 and 2.5 mg/kg.

1398609-39-6

Chemical Properties

Safety Data

Hazard Information

Uses

in vivo

Spectrum Detail

Supplier