137641-05-5

Herbicide.

ChEBI: Picolinafen is a pyridinecarboxamide resulting from the formal condensation of the carboxy group of 6-(m-trifluoromethylphenoxy)picolinic acid with the amino group of p-fluoroaniline. A carotenoid biosynthesis inhibitor, it is used as a herbicide for the control of broad-leaved weeds in cereal crops. It has a role as a herbicide, an agrochemical and a carotenoid biosynthesis inhibitor. It is a pyridinecarboxamide, a member of (trifluoromethyl)benzenes, an aromatic ether and a member of monofluorobenzenes.

The industrial synthesis of picolinafen begins with the preparation of the trifluoromethylphenol derivative, which undergoes etherification with a halogenated picolinic acid precursor to form the phenoxy linkage. This step is typically carried out in polar aprotic solvents like DMF or DMSO under basic conditions. The methyl group is introduced via alkylation, and the final product is purified through crystallisation or solvent extraction.

Selective, with rapid foliar absorption. Bleaching - Carotenoid biosynthesis inhibitor

Herbicide