13738-63-1

Moderately toxic by ingestion.

Fluoronitrofen was produced through a straightforward but tightly controlled sequence typical of early diphenyl-ether herbicides. Manufacturers first generated the fluorinated phenoxy precursor, usually by nitrating a fluorinated anisole or related aromatic ether under mixed acid conditions, followed by selective coupling with a chloronitrophenyl moiety using halogen-metal exchange or nucleophilic aromatic substitution routes that favoured formation of the diphenyl-ether bond. The crude active ingredient was then purified by solvent washing and recrystallisation to remove unreacted nitroaromatics and by-products, yielding a technical grade solid.

Protoporphyrinogen oxidase inhibitor

Herbicide