General Description
Clear colorless liquids with a strong unpleasant odor. Flash point 79-97°F. Less dense than water. Vapors heavier than air. Toxic oxides of nitrogen produced during the combustion of. Used as a solvent and to make other chemicals.
Reactivity Profile
GAMMA PICOLINE or 4-METHYLPYRIDINE neutralizes acids in exothermic reactions to form salts plus water. PICOLINES(1333-41-1) is incompatible with isocyanates, halogenated organics, peroxides, phenols, sulfuric acid, epoxides, anhydrides, acid halides and Iron (II) sulfate. Gamma picoline may generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. Dangerous fire hazard when exposed to heat, flame or oxidizers. Severe explosion hazards in the form of vapor, when exposed to flame or spark. Reacts violently with chlorosulfonic acid; CrO3; maleic anhydride; HNO3; oleum; perchromates; B-propiolactone; AgClO4; H2SO4;formamide; SO3; I. Dangerous when heated to decomposition PICOLINES(1333-41-1) emits highly toxic fumes of cyanides; can react vigorously with oxidizing materials.
Air & Water Reactions
Highly flammable. Soluble in water.
Health Hazard
Harmful if swallowed, inhaled or absorbed through the skin. Causes severe irritation. High concentrations are extremely destructive to tissues of the mucous membranes and upper respiratory tract, eyes and skin. Symptoms of exposure may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, vomiting and gastrointestinal disturbances.
Potential Exposure
(o-isomer); Suspected reprotoxic hazard, Primary irritant (w/o allergic reaction), (m-isomer): Possible risk of forming tumors, Primary irritant (w/o allergic reaction). Picolines are used as intermediates in pharmaceutical manufacture, pesticide manufacture; and in the manufacture of dyes and rubber chemicals. It is also used as a solvent.
Fire Hazard
Special Hazards of Combustion Products: Emits toxic fumes under fire conditions. Forms explosive mixture in air.
First aid
If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Speed in removing material from skin is of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit.
Shipping
UN2313 Picolines, Hazard Class: 3; Labels: 3-Flammable liquid.
Incompatibilities
Vapors may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Attacks copper and its alloys.
Chemical Properties
Picolines are colorless liquids. Strong, unpleasant, pyridine-like odor.“Picoline” is often used as mixed isomers.
Definition
ChEBI: 2-methylpyridine is a methylpyridine carrying a methyl substituent at position 2.
