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131-57-7

Name Oxybenzone
CAS 131-57-7
EINECS(EC#) 205-031-5
Molecular Formula C14H12O3
MDL Number MFCD00008387
Molecular Weight 228.24
MOL File 131-57-7.mol

Chemical Properties

Appearance white to light yellow crystalline powder
Melting point  62-64 °C(lit.)
Boiling point  150-160 °C5 mm Hg(lit.)
density  1,3 g/cm3
vapor pressure  0.001Pa@25°C
refractive index  1.5805 (estimate)
Fp  216°C
storage temp.  2-8°C
solubility  95% ethanol: soluble50mg/mL, clear, colorless
form  Crystalline Powder
pka 7.56±0.35(Predicted)
color  White to light yellow
Odor ylsh. cryst., rose-like odor
Water Solubility  <0.1 g/100 mL at 20 ºC
Merck  14,6954
BRN  1913145
Contact allergens
BZP-3 is used as a direct sunscreen agent and in antiaging creams. Allergic reactions have been reported. Cross-reactivity is expected in an average of one in four patients photoallergic to ketoprofen.
InChIKey DXGLGDHPHMLXJC-UHFFFAOYSA-N
LogP 3.45 at 40℃
Uses
benzophenone-3 (oxybenzone) is an oil-soluble uV absorber and filter with absorption rates within the uVA and uVB peak ranges. It has an approved usage level of up to 6 percent in the united States and 10 percent in the european union. Benzophenone-3 enhances SPF and is popular among sunscreen formulators given a concern over potential safety problems associated with more traditional sunscreen chemicals. However, some reports associate it with causing photocontact allergy. It is considered a non-comedogenic raw material.
CAS DataBase Reference 131-57-7(CAS DataBase Reference)
NIST Chemistry Reference Oxybenzone(131-57-7)
EPA Substance Registry System 131-57-7(EPA Substance)

Safety Data

Hazard Codes  Xi
Risk Statements 
R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
RIDADR  UN 3077 9/PG III
WGK Germany  2
RTECS  DJ1575000
TSCA  Yes
HazardClass  9
PackingGroup  III
HS Code  29145000
Safety Profile
Poison by intraperitoneal route. Mddly toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazardous Substances Data 131-57-7(Hazardous Substances Data)
Toxicity
LD50 orally in rats: >12.8 g/kg (Lewerenz)

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