1269802-97-2

NHI 2 is an inhibitor of lactate dehydrogenase A (LDHA; IC₅₀ = 14.7 μM). It is selective for LDHA over LDHB (IC₅₀ = 55.8 μM). It inhibits lactate production in HeLa cells when used at concentrations of 100 and 200 μM. NHI 2 is cytotoxic to HeLa cells (IC₅₀ = 33.4 μM).

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