ChemicalBook CAS DataBase List 1268709-57-4

1268709-57-4

Name	CAY10678
CAS	1268709-57-4
Molecular Formula	C23H34N4O
Molecular Weight	382.54
MOL File	1268709-57-4.mol

Chemical Properties

storage temp.	Store at -20°C
solubility	DMF: 15 mg/ml; DMSO: 5 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS (pH 7.2) (1:8): 0.1 mg/ml
form	A crystalline solid
color	White to off-white

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Shanghai Aladdin Bio-Chem Technology Co.,LTD

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Nanjing Dulai Biotechnology Co., Ltd.

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Shanghai EFE Biological Technology Co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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Shanghai Chaolan Chemical Technology Center

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Career Henan Chemica Co

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Shanghai Dongyang Biotechnology Co., Ltd.

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Energy Chemical

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Jinan Jiuli Biotechnology Co. , Ltd.

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Shanghai Universal Biotech Co.,Ltd

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Bide Pharmatech Ltd.

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TargetMol Chemicals Inc.

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Nantong QuanYi Biotechnology Co., Ltd

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Shanghai Chengrui Biotechnology Co., Ltd

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Animal Model:	1% Carrageenan stimulated mouse air pouch model^[1]
Dosage:	10, 50, 100 mg/kg
Administration:	ip; single dose after modeling: use 3 mL of sterile-filtered air was injected sub-cutaneously into the interscapular region of mice; triggered in the pouch 24 h later by the injection of a 1 ml solution of λ-carrageenan (1%) in saline.
Result:	Had no effect on inflammatory exudate volume but dose-dependently reduced cell migration. Resulted in a decrease in PGE2 synthesis, it does not affect changes in other prostaglandin levels, but leads to an overall downregulation of prostaglandin synthesis.

1268709-57-4

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