GENERAL STEPS: Compound I-8 (50 g, 140 mmol) and 2-([1,1':3',1''-terphenyl]-5'-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (43.7 g, 154 mmol) were dissolved in 0.45 L of tetrahydrofuran (THF), and tetrakis(triphenylphosphine)palladium was added under nitrogen protection ( 1.62 g, 1.40 mmol). Subsequently, saturated aqueous potassium carbonate solution (48.4 g, 350 mmol) was added and the reaction mixture was heated to reflux at 80 °C for 12 hours. After completion of the reaction, the reaction solution was poured into water and the organic phase was extracted with dichloromethane (DCM). The organic phase was dried with anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure. The resulting residue was purified by fast column chromatography to afford the target product 3-bromo-5'-phenyl-1,1':3',1''-terphenyl (Compound I-15, 41.5 g, 77% yield).
![2-([1,1':3',1''-terphenyl]-5'-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane](/CAS/20180703/GIF/1036378-83-2.gif)
