Description
Pydiflumetofen is a broad-spectrum fungicide. It has a low aqueous solubility and a low volatility. It may be persistent in both soil and water systems depending upon local conditions. It is not highly toxic to mammals but it may be a liver and/or thyroid toxicant. It is highly toxic to most aquatic species.
Uses
Pydiflumetofen is used in the preparation of carboxamides as plant growth enhancers in crops.
Definition
ChEBI: 3-(difluoromethyl)-N-methoxy-1-methyl-N-[1-(2,4,6-trichlorophenyl)propan-2-yl]pyrazole-4-carboxamide is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of N-methoxy-1-(2,4,6-trichlorophenyl)propan-2-amine. It is a trichlorobenzene, a monocarboxylic acid amide, an aromatic amide, a member of pyrazoles and an organofluorine compound.
Mechanism of action
Succinate Dehydrogenase Inhibitor (SDHI)
Synthesis
The preparation method of pydiflumetofen comprises the following steps: (1) performing a reaction on p-chloroaniline and isopropenyl acetate to obtain 4'-chloropropiophenone; (2) performing benzene ring chlorination to obtain 2',4',6'-trichloropropiophenone; (3) performinga carbonyl reduction reaction to obtain 1-(2',4',6'-trichlorophenyl)-2-propanol; (4) performing hydroxyl halogenation to obtain 1-(2',4',6-trichlorophenyl)-2-chloropropane; (5) performing amination on 1-(2,4,6-trichlorophenyl)-2-chloropropane and O-methylhydroxylamine to obtain O-methyl N-[1-methyl-2-(2,4,6-trichlorophenyl)-ethyl]-hydroxylamine; (6) performing a substitution reaction on the product obtained in step (5) and 3-difluoromethyl-1-methyl-1H-pyrazole-4-carbonyl chloride under the action of an acid binding agent to obtain pydiflumetofen.
Pesticide Type
Fungicide; Plant Growth Regulator
