1223284-75-0

KY-04045 is a PAK4 inhibitor.

KY-04045 is a PAK4 specific inhibitor (IC50=8.7 μM) that can be used for the development of anticancer drugs targeting PAK4[1].

PAK4: 8.7 μM (IC₅₀)

[1] Park, et al. "The discovery and the structural basis of an imidazo [4, 5-b] pyridine-based p21-activated kinase 4 inhibitor." Bioorganic & medicinal chemistry letters 26.11 (2016): 2580-2583. DOI:10.1016/j.bmcl.2016.04.037