122296-00-8

mp 55–56 °C.

New Benzotriazole Reagents

Reactant for:

• Alkylation reactions
• Preparation of inhibitor of p53-MDM2 complex formation

• Used as a one-carbon synthon for one-carbon homologation of carboxylic acids

1-[(Trimethylsilyl)methyl]- 1H-benzotriazole is a reagent in the preparation of ketones, carboxylic acids,One-carbon Homologation of Carboxylic Acids,Synthesis of Fused Heterocycles and fused heterocycles.

1-[(trimethylsilyl)methyl]-1H-benzotriazole is readily prepared in a reaction of sodium benzotriazolide with chloromethyltrimethylsilane.