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Calpinactam is a fungal metabolite with antimycobacterial activity. It is active against M. smegmatis.

Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively[1].

Fungal Metabolite

+4°C

[1] Nobuhiro Koyama, et al.Calpinactam, a new anti-mycobacterial agent, produced by Mortierella alpina FKI-4905. J Antibiot (Tokyo). 2010 Apr;63(4):183-6. DOI:10.1038/ja.2010.14