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Retinol-d5 — biologically active form of fat-soluble vitamin A, with a stable deuterium label for quantitative studies by mass spectrometric methods. Retinol-d5 can be used to study the absorption, distribution and excretion of vitamin A in humans and animals, to study various physiological processes, including gene regulation, cell differentiation and immune function.

all-trans-Retinol-d5 is a labeled analog of all-trans-Retinol (R252000), which occurs preformed only in animals; metabolized from carotenoids, such β-carotene, in the intestinal mucosa. Dietary sources include liver, milk, butter, cheese, eggs and fish liver oils or as carotenois from fruits and vegetables. Stored primarily in the liver in esterified form; transported in the blood by retinol binding protein (RBP). Nutritional factor.