1166-01-4

Name	3' 4'-DICHLOROBENZAMIL
CAS	1166-01-4
Molecular Formula	C13Cl3H12N7O1
MDL Number	MFCD03425383
Molecular Weight	425.1
MOL File	1166-01-4.mol

Synonyms

Dichlorobenzamil 3' 4'-DICHLOROBENZAMIL 4'-Dichlorobenzamil HCl 3',4'-Dichlorobenzamil HCl 3',4' Dichlorobenzamil HCl,3',4'Dichlorobenzamil HCl 3,5-diamino-6-chloro-N-[N'-(3,4-dichlorobenzyl)carbamimidoyl]pyrazinamide 3,5-diamino-6-chloro-N-[N'-[(3,4-dichlorophenyl)methyl]carbamimidoyl]pyrazine-2-carboxamide N-[Imino[(3,4-dichlorophenylmethyl)amino]methyl]-3,5-diamino-6-chloro-2-pyrazinecarboxamide 3,5-Diamino-6-chloro-N-[[(3,4-dichlorophenyl)methylamino](imino)methyl]-2-pyrazinecarboxamide 3,5-bis(azanyl)-6-chloro-N-[N'-[(3,4-dichlorophenyl)methyl]carbamimidoyl]pyrazine-2-carboxamide

show less show more

Chemical Properties

storage temp.	2-8°C
solubility	DMSO: 30 mg/mL, soluble
form	solid
color	yellow

Safety Data

WGK Germany

Hazard Information

Uses

Dichlorobenzamil (3',4'-Dichlorobenzamil; L-594881) is an effective Na/Ca exchange inhibitor. Dichlorobenzamil significantly inhibits 45Ca uptake mediated by reverse Na/Ca exchange in pancreatic islet cells (IC50 = 18 μM). Dichlorobenzamil can also block K+ channels and voltage-sensitive Ca2+ channels[1].

Definition

ChEBI: 3,5-diamino-N-[amino-[(3,4-dichlorophenyl)methylimino]methyl]-6-chloro-2-pyrazinecarboxamide is a member of pyrazines and a member of guanidines.

References

[1] Plasman P O, et al. Inhibition of Na/Ca exchange in pancreatic islet cells by 3′, 4′-dichlorobenzamil[J]. Biochemical pharmacology, 1991, 41(11): 1759-1768. DOI:10.1016/0006-2952(91)90181-4

Supplier

Shaanxi Dideu Medichem Co. Ltd

Telephone+86-29-81148696 +86-17392712697

Websitehttps://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-221/

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Related Products

2016-88-8

PROMPT×

PROMPT
The What'sApp is temporarily not supported in mainland China

Cancel

Determine

Send Inquriy