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2016-88-8

Supplier Related Products Identification Chemical Properties Safety Data Raw materials And Preparation Products Hazard Information Material Safety Data Sheet(MSDS) Well-known Reagent Company Product Information

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Identification

Name
Amiloride hydrochloride
CAS
2016-88-8
Synonyms
3,5-DIAMINO-6-CHLORO-N-(DIAMINOMETHYLIDENE)PYRAZINE-2-CARBOXAMIDE
3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLOROPYRAZINECARBOXAMIDE HYDROCHLORIDE
3,5-DIAMINO-N-(AMINOMETHYL)-6-CHLOROPYRAZINE CARBOXAMIDE HYDROCHLORIDE
AMILORIDE HCL
AMILORIDE HCL HYDRATE
AMILORIDE HYDROCHLORIDE
AMILORIDE HYDROCHLORIDE HYDRATE
AMIPRAMIDIN
AMIPRAMIZIDE
GUANAMPRAZINE
N-AMIDINO-3,5-DIAMINO-6-CHLOROPYRAZINECARBOXAMIDE HYDROCHLORIDE
amiloridechloride
amiprazidine
n-amidino-3,5-diamino-6-chloro-pyrazinecarboxamidmonohydrochloride
N-amidino-3,5-diamino-6-chloropyrazinecarboxamide monohydrochloride
HCL AMILORIDE HCL
Amipramidin hydrochloride
Amipramizide hydrochloride
Guanamprazine hydrochloride
Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride
EINECS(EC#)
217-958-2
Molecular Formula
C6H11Cl2N7O2
MDL Number
MFCD03703482
Molecular Weight
284.1
MOL File
2016-88-8.mol

Chemical Properties

mp 
293-294°C
solubility 
H2O: 50 mg/mL, clear, yellow-green

form 
powder

color 
yellow

Water Solubility 
<0.1 g/100 mL at 19.5 ºC
CAS DataBase Reference
2016-88-8(CAS DataBase Reference)
EPA Substance Registry System
2016-88-8(EPA Substance)

Safety Data

Hazard Codes 
T,Xi
Risk Statements 
R25:Toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Statements 
S36:Wear suitable protective clothing .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
RIDADR 
UN 2811 6.1/PG 3

WGK Germany 
3

RTECS 
UQ2275500

HazardClass 
6.1(a)
PackingGroup 
II

Raw materials And Preparation Products

Hazard Information

General Description
Crystalline solid or very light yellow powder.
Reactivity Profile
A halogenated amine and amide, acidic salt. In aqueous solution, behaves as a weak acid. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Air & Water Reactions
Insoluble in water.
Health Hazard
SYMPTOMS: Symptoms of exposure to this compound include headache, weakness, fatigue, back, chest, neck, shoulder or extremity pain; nausea, anorexia, vomiting, abdominal pain, hyperkalemia, paresthesias, shock, dizziness, coughing, shortness of breath, depression, nervousness, flaccid paralysis of the extremities, bradycardia, flatulence, skin rash, gas pain, constipation and dyspnea.
Fire Hazard
Flash point data for this material are not available; however, AMILORIDE HYDROCHLORIDE(2016-88-8) is probably combustible.

Material Safety Data Sheet(MSDS)

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